Ca-D Glucarate

Description

Basic concepts and physiologic function, D-glucaric acid is naturally found within the human body and is also present in some foods, particularly vegetables. D-glucaric acid plays an important role in the detoxification process, by promoting the conjugation of endogenous substances such as hormones and exogenous substances such as pollution so that these substances can then be excreted in the bile or urine. Secondly, a metabolite of D-glucaric acid inhibits the enzyme beta-glucaronidase which would otherwise cleave detoxified poisons from their hydrophilic conjugate, allowing the intestinal reabsorption of the toxin.